To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02139
Peptide Name Simplicilliumtide J
Sequence XIXYQPXAXTX
Sequence Length 6
UniProt ID None
Taxon ID None
Source Fungus Simplicillium obclavatum EIODSF 0210
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HSV-1
Assay Anti-HSV-Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism Not Available
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Cyclic
N-terminal Modification Free
C-terminal Modification Free
Other Modification X at position 1: allo-Ile,X at position 2: D-Tyr,X at position 5: D-Ala,X at position 6: D-allo-Thr,X at position 7: 5(S)-HTA (non-standard residue)
Stereochemistry L
Physicochemical Information
Formula C25H30N4O5
Absent amino acids RNDCEGHLKMFSVOU
Common amino acids A
Mass 691.78
Pl 5.52
Basic residues 0
Acidic residues 0
Hydrophobic residues 6
Net charge 0
Boman Index 0.92
Hydrophobicity -0.133
Aliphatic Index 81.67
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 2.154
Polar residues 6
Literature Information
Literature 1
Title Antifungal and Antiviral Cyclic Peptides from the Deep-Sea-Derived Fungus Simplicillium obclavatum EIODSF 020
Pubmed ID 28578573
Reference Journal of agricultural and food chemistry, 65(25), 5114–5121.
Author Liang, X., Nong, X. H., Huang, Z. H., & Qi, S. H. (2017).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.