General Information
DRAVP ID DRAVPe02146
Peptide Name Valinomycin; streptodepsipeptides P11A and SV21
Sequence AVVVDAVVVDAVVVDAVVVD
Sequence Length 20
UniProt ID None
Taxon ID None
Source Bacterial symbiont Streptomyces sp. SV21
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HCV
Assay Anti-HCV assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism viral surface, due to the presence of hydrophobic amino acid
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Cyclic
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C54H90N6O18
Absent amino acids RNCQEGHHILKMFPSTWYOU
Common amino acids V
Mass 1952.28
Pl 3.32
Basic residues 0
Acidic residues 4
Hydrophobic residues 10
Net charge -4
Boman Index 0.96
Hydrophobicity 2.18
Aliphatic Index 194
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 12
Literature Information
Literature 1
Title Anti-Infective and Antiviral Activity of Valinomycin and Its Analogues from a Sea Cucumber-Associated Bacterium, Streptomyces sp. SV 21
Pubmed ID 33540548
Reference Marine drugs, 19(2), 81.
Author Wibowo, J. T., Kellermann, M. Y., Köck, M., Putra, M. Y., Murniasih, T., Mohr, K. I., Wink, J., Praditya, D. F., Steinmann, E., & Schupp, P. J. (2021).