To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02160
Peptide Name Octapeptide
Sequence AVLQSGFR
Sequence Length 8
UniProt ID P0C6U8
Taxon ID 694009
Source Structure of SARS-CoV Mpro
Validation Experimentally Validated
Origin Information
Gene Name/ID 1a
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SARS-CoV
Assay Cell–Cell Fusion Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not Found
Mechanism It inhibits replication
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C39H64N12O11
Absent amino acids NDCEHIKMPTWYOU
Common amino acids ARQGLFSV
Mass 877.01
Pl 9.79
Basic residues 1
Acidic residues 0
Hydrophobic residues 8
Net charge 1
Boman Index 1.1
Hydrophobicity 0.425
Aliphatic Index 97.5
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 6
Literature Information
Literature 1
Title Synthesis and activity of an octapeptide inhibitor designed for SARS coronavirus main proteinase
Pubmed ID 16242214
Reference Peptides, 27(4), 622–625.
Author Gan, Y. R., Huang, H., Huang, Y. D., Rao, C. M., Zhao, Y., Liu, J. S., Wu, L., & Wei, D. Q. (2006).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.