To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02161
Peptide Name 6a
Sequence LQQFMK
Sequence Length 6
UniProt ID None
Taxon ID None
Source Cleavage site of SARS-CoV Mpro
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SARS-CoV
Assay Cell–Cell Fusion Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not Found
Mechanism Not Available
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C36H59N9O9S1
Absent amino acids ARNDCEGHIPSTWYVOU
Common amino acids Q
Mass 793.98
Pl 8.75
Basic residues 1
Acidic residues 0
Hydrophobic residues 6
Net charge 1
Boman Index 1.08
Hydrophobicity 8.75
Aliphatic Index 65
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 6
Literature Information
Literature 1
Title Design and synthesis of dipeptidyl glutaminyl fluoromethyl ketones as potent severe acute respiratory syndrome coronovirus (SARS-CoV) inhibitors
Pubmed ID 16451084
Reference J. Med. Chem. 2006, 49, 3, 1198–1201
Author Zhang, H. Z., Zhang, H., Kemnitzer, W., Tseng, B., Cinatl, J., Jr, Michaelis, M., Doerr, H. W., & Cai, S. X. (2006).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.