To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02162
Peptide Name Protected tetrapeptide
Sequence AVLQ
Sequence Length 4
UniProt ID None
Taxon ID None
Source Cleavage site of the main proteases
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SARS-CoV
Assay Peptide cleavage assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Found
Mechanism Not Available
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification carboxybenzyl
C-terminal Modification nitrile
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C19H36N6O6
Absent amino acids NDCFPSTWYVOUMGK
Common amino acids Q
Mass 432.53
Pl 6.02
Basic residues 0
Acidic residues 0
Hydrophobic residues 3
Net charge 0
Boman Index 0.37
Hydrophobicity 0.875
Aliphatic Index 117.5
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Literature Information
Literature 1
Title Profiling of substrate-specificity and rational design of broad-spectrum peptidomimetic inhibitors for main proteases of coronaviruses
Pubmed ID 25224114
Reference Hong Kong medical journal = Xianggang yi xue za zhi, 20 Suppl 4, 22–25.
Author Chuck, C. P., Ke, Z. H., Chen, C., Wan, D. C., Chow, H. F., & Wong, K. B. (2014).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.