To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02163
Peptide Name Peptide aldehyde 1
Sequence ESTLQ
Sequence Length 5
UniProt ID None
Taxon ID None
Source Analyses of the SARS-CoV Mpro
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SARS-CoV
Assay Peptide cleavage assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Found
Mechanism tight-binding inhibitors
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Hydogenation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C23H40N6O11
Absent amino acids ANDCFPWYVOU
Common amino acids QELST
Mass 576.6
Pl 4
Basic residues 0
Acidic residues 1
Hydrophobic residues 5
Net charge -1
Boman Index 1.152
Hydrophobicity -0.94
Aliphatic Index 78
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Literature Information
Literature 1
Title Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease
Pubmed ID 21854807
Reference Antiviral research, 92(2), 204–212.
Author Vilas Boas, L. C., de Lima, L. M., Migliolo, L., Mendes, G. D., de Jesus, M. G., Franco, O. L., & Silva, P. A. (2017).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.