To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02167
Peptide Name Tetrapeptide aldehyde
Sequence TVFH
Sequence Length 4
UniProt ID None
Taxon ID None
Source Analyses of the SARS-CoV 3CL protease
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SARS-CoV
Assay Cell–Cell Fusion Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Found
Mechanism Not Available
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Not included yet
C-terminal Modification Not included yet
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C25H37N5O6
Absent amino acids ARNDCEGILMSPTWYOU
Common amino acids TVFH
Mass 522.61
Pl 7.52
Basic residues 1
Acidic residues 0
Hydrophobic residues 2
Net charge 1
Boman Index 0.79
Hydrophobicity 0.425
Aliphatic Index 97.5
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Literature Information
Literature 1
Title Structure-based design, synthesis, and evaluation of peptide-mimetic SARS 3CL protease inhibitors
Pubmed ID 22014094
Reference Journal of medicinal chemistry, 54(23), 7962–7973.
Author Akaji, K., Konno, H., Mitsui, H., Teruya, K., Shimamoto, Y., Hattori, Y., Ozaki, T., Kusunoki, M., & Sanjoh, A. (2011).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.