General Information
DRAVP ID DRAVPe02174
Peptide Name K12
Sequence GGASCCLYCRCH
Sequence Length 12
UniProt ID P0C6U8
Taxon ID 694009
Source Sequence of nsp 10 of SARS-CoV
Validation Experimentally Validated
Origin Information
Gene Name/ID 1a
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SARS-CoV
Assay Not Available
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Found
Mechanism Not Available
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C49H77N17O15S4
Absent amino acids NDQEIKMFPTWVOU
Common amino acids C
Mass 1272.5
Pl 7.9
Basic residues 1
Acidic residues 0
Hydrophobic residues 10
Net charge 1
Boman Index 0.633
Hydrophobicity 0.417
Aliphatic Index 40.83
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 1.171
Polar residues 12
Literature Information
Literature 1
Title Short peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2'-O-methyltransferase activity of nsp10/nsp16 complex
Pubmed ID 22659295
Reference Virus research, 167(2), 322–328.
Author Ke, M., Chen, Y., Wu, A., Sun, Y., Su, C., Wu, H., Jin, X., Tao, J., Wang, Y., Ma, X., Pan, J. A., & Guo, D. (2012).