General Information
DRAVP ID DRAVPe02175
Peptide Name K29
Sequence FGGASCCLYCRCHIDHPNPKGFCDLKGKY
Sequence Length 29
UniProt ID P0C6U8
Taxon ID 694009
Source Sequence of nsp 10 of SARS-CoV
Validation Experimentally Validated
Origin Information
Gene Name/ID 1a
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SARS-CoV
Assay Not Available
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Found
Mechanism Not Available
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C141H210N40O38S5
Absent amino acids QEMWVOU
Common amino acids C
Mass 3233.76
Pl 8.4
Basic residues 4
Acidic residues 2
Hydrophobic residues 18
Net charge 2
Boman Index 0.918
Hydrophobicity -0.321
Aliphatic Index 43.78
Half Life
Extinction Coefficient cystines 2980
Absorbance 280nm 0.922
Polar residues 22
Literature Information
Literature 1
Title Short peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2'-O-methyltransferase activity of nsp10/nsp16 complex
Pubmed ID 22659295
Reference Virus research, 167(2), 322–328.
Author Ke, M., Chen, Y., Wu, A., Sun, Y., Su, C., Wu, H., Jin, X., Tao, J., Wang, Y., Ma, X., Pan, J. A., & Guo, D. (2012).