To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02177
Peptide Name F
Sequence FKPSSPPSITLW
Sequence Length 12
UniProt ID None
Taxon ID None
Source S protein of TGEV (synthetic Construct)
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism TGEV
Assay ELISA
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target S protein
Mechanism The peptides showed an effective binding to pAPN and inhibition to TGEV infection, although their sequences are not completely identical to the homologous regions in the S1 protein
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C66H98N14O17
Absent amino acids ARNDCQEGHMYVOU
Common amino acids PS
Mass 1359.59
Pl 8.75
Basic residues 1
Acidic residues 0
Hydrophobic residues 10
Net charge 1
Boman Index 0.9
Hydrophobicity -0.133
Aliphatic Index 65
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 4.045
Polar residues 12
Literature Information
Literature 1
Title Phage displayed peptides recognizing porcine aminopeptidase N inhibit transmissible gastroenteritis coronavirus infection in vitro
Pubmed ID 21176936
Reference Virology, 410(2), 299–306.
Author Ren, X., Liu, B., Yin, J., Zhang, H., & Li, G. (2011).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.