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General Information
DRAVP ID DRAVPe02208
Peptide Name BetaWWI-1
Sequence IWWVVV
Sequence Length 6
UniProt ID No entry found
Taxon ID None
Source HIV gp41 C-terminus (C-peptides)
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HIV,EBOV
Assay HIV infectivity assays
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Glycoprotein.
Mechanism Inhibit viral fusion with host cell by intramolecular protein-protein interactions.
Structure Information
PDB ID None
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C43H60N8O7
Absent amino acids ARNDCQEGHLKMFPSTYOU
Common amino acids V
Mass 801
Pl 5.52
Basic residues 0
Acidic residues 0
Hydrophobic residues 6
Net charge 0
Boman Index -3.61
Hydrophobicity 2.55
Aliphatic Index 210
Half Life
Extinction Coefficient cystines 11000
Absorbance 280nm 13.733
Polar residues 0
Literature Information
Literature 1
Title Inhibiting HIV fusion with a beta-peptide foldamer.
Pubmed ID 16173723
Reference J Am Chem Soc. 2005;127(38):13126-7.
Author Stephens OM, Kim S, Welch BD, et al.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.