DRAVP ID  DRAVPe02214

Peptide Name   Alloferon-1

Sequence  HGVSGHGQHGVHG

Sequence Length  13

UniProt ID  P83412 

Taxon ID  7373 

Source  Calliphora vicina (Blue blowfly) (Calliphora erythrocephala)

Validation   Experimentally Validated

Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  1 to 13

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available

Target Organism  IAV,IBV, HHV-1

Assay  Antiviral Assay

Activity 

• [Ref:21766388] HHV:inhibited the Human Herpes Virus type 1 (HHV-1) multiplication

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not found

Mechanism  Not Available

PDB ID  None

Predicted Structure Download 

Linear/Cyclic  Cyclic

N-terminal Modification  Amination

C-terminal Modification  Free

Other Modification  the N-terminal amine, the three imidazoles of H1, H6, and H9 participate in the coordination of Zn(II)

Stereochemistry  L

Literature 1

Title   Antiviral and antitumor peptides from insects;

Pubmed ID   12235362

Reference   Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12628-32;

Author   Chernysh S, Kim SI, Bekker G, Pleskach VA, Filatova NA, Anikin VB, Platonov VG, Bulet P;

DOI   10.1073/pnas.192301899;