General Information


DRAVP ID  DRAVPe02222

Peptide Name   RVFV-8

Sequence  SWNFFDWFSGLMSWFGGPLK

Sequence Length  20

UniProt ID  P03518  P21403 

Taxon ID  11588 

Source  Rift Valley fever virus (RVFV) Gc stem region

Validation   Not experimentally validated



Origin Information


Gene Name/ID  GP

GenBank  Not Available

Amino Acid position  1139-1158

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  EBOV

Assay  Virus inhibition assays

Activity  Not Available

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not found

Mechanism  Not Available



Structure Information


PDB ID  6EGT 

Predicted Structure Download 

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  C120H153N25O27S1

Absent amino acids  ARCQETVOU

Common amino acids  F

Mass  2409.75

Pl  5.55

Basic residues  1

Acidic residues  1

Hydrophobic residues  10

Net charge  0

Boman Index  -0.14

Hydrophobicity  0.095

Aliphatic Index  39

Half Life 

  •     Mammalian:1.9 hours
  •     Yeast:>20 hours
  •     E.coli:>10 hours

Extinction Coefficient cystines  16500

Absorbance 280nm  6.847

Polar residues  4



Literature Information


Literature 1

Title   A fusion-inhibiting peptide against Rift Valley fever virus inhibits multiple, diverse viruses

Pubmed ID   24069485

Reference   PLoS Negl Trop Dis. 2013;7(9):e2430.

Author   Koehler JW, Smith JM, Ripoll DR, et al.

DOI   10.1371/journal.pntd.0002430