To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02225
Peptide Name Brevinin-1
Sequence FLPVLAGIAAKVVPALFCKITKKC
Sequence Length 24
UniProt ID P32423
Taxon ID None
Source frog, Rana brevipoda porsa, Japan, Asia
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HSV
Assay Virus inhibition assays
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism Not Available
Structure Information
PDB ID None
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Cyclization (Cys18 and Cys24)
Other Modification Disulfide bond between Cys18 and Cys24.
Stereochemistry L
Physicochemical Information
Formula C121H204N28O26S2
Absent amino acids DEHMNQRSWY
Common amino acids AK
Mass 2531.24
Pl 9.7
Basic residues 4
Acidic residues 0
Hydrophobic residues 14
Net charge 4
Boman Index 28.65
Hydrophobicity 1.288
Aliphatic Index 134.17
Half Life
Extinction Coefficient cystines 125
Absorbance 280nm 5.43
Polar residues 4
Literature Information
Literature 1
Title Evaluation of the inactivation of infectious Herpes simplex virus by host-defense peptides
Pubmed ID 10795591
Reference official publication of the European Society of Clinical Microbiology, 19(3), 187–194.
Author Yasin, B., Pang, M., Turner, J. S., Cho, Y., Dinh, N. N., Waring, A. J., Lehrer, R. I., & Wagar, E. A. (2000).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.