To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02226
Peptide Name Dermaseptin-3
Sequence ALWKNMLKGIGKLAGKAALGAVKKLVGAES
Sequence Length 30
UniProt ID P80279
Taxon ID None
Source Phyllomedusa sauvagei (Sauvage's leaf frog)
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HIV-1
Assay Not Available
Activity Not Available
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism Not Available
Structure Information
PDB ID None
Linear/Cyclic Linear
N-terminal Modification Cyclization (N termini to C termini)
C-terminal Modification Cyclization (N termini to C termini)
Other Modification Disulfide bonds between Cys4 and Cys20; Cys8 and Cys22; Cys13 and Cys27.
Stereochemistry L
Physicochemical Information
Formula C133H215N37O39S6
Absent amino acids DFHLMQT
Common amino acids C
Mass 3148.75
Pl 8.33
Basic residues 3
Acidic residues 1
Hydrophobic residues 9
Net charge 2
Boman Index -9
Hydrophobicity 0.53
Aliphatic Index 78
Half Life
Extinction Coefficient cystines 7365
Absorbance 280nm 253.97
Polar residues 15
Literature Information
Literature 1
Title The Vertebrate Peptide Antibiotics Dermaseptins Have Overlapping Structural Features but Target Specific Microorganisms
Pubmed ID 7989335
Reference J Biol Chem. 1994;269(50):31635-31641
Author Mor A, Hani K, Nicolas P. 1994
DOI N/A
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.