To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02237
Peptide Name C18-s2
Sequence ARLPRTMVHPKPAQP
Sequence Length 15
UniProt ID No entry found
Taxon ID None
Source Synthetic construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism Influenza A H1N1/A/Puerto Rico/8 (H1N1)
Assay Plaque reduction
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Binding the head of HA (protein present at the out membrane of the virus)
Mechanism Interfering with the fusogenic activity of HA.
Structure Information
PDB ID None
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification C17H35CO
Stereochemistry L
Physicochemical Information
Formula C75H127N25O18S1
Absent amino acids NDCEGIFSYOU
Common amino acids P
Mass 1699.05
Pl 12.01
Basic residues 3
Acidic residues 0
Hydrophobic residues 5
Net charge 3
Boman Index 2.21
Hydrophobicity -0.88
Aliphatic Index 58.67
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Literature Information
Literature 1
Title Sialic acid-mimic peptides as hemagglutinin inhibitors for anti-influenza therapy
Pubmed ID 20476787
Reference Journal of medicinal chemistry, 53(11), 4441–4449.
Author Matsubara, T., Onishi, A., Saito, T., Shimada, A., Inoue, H., Taki, T., Nagata, K., Okahata, Y., & Sato, T. (2010).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.