To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02244
Peptide Name PeBGF
Sequence ARDFYGYDVFFYAMD
Sequence Length 15
UniProt ID No entry found
Taxon ID None
Source Synthetic construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism Influenza A H3N2/A/Aichi/2/68 X31 (H3N2)
Assay Infection inhibition
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Head of HA
Mechanism The most interesting peptide was the PeBGF, which showed a micromolar activity in SPR, HI, neutralization, and infection inhibition assays toward both Aichi H3N2 and Rostock H7N1 viral strains
Structure Information
PDB ID None
Linear/Cyclic Linear
N-terminal Modification Not included yet
C-terminal Modification Not included yet
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C90H114N18O25S1
Absent amino acids NQEHILKMPSTWOU
Common amino acids DFY
Mass 1880.06
Pl 3.93
Basic residues 1
Acidic residues 3
Hydrophobic residues 7
Net charge -2
Boman Index 1.44
Hydrophobicity -0.08
Aliphatic Index 32.67
Half Life
Extinction Coefficient cystines 4470
Absorbance 280nm 2.378
Polar residues 3
Literature Information
Literature 1
Title Anti-Hemagglutinin Antibody Derived Lead Peptides for Inhibitors of Influenza Virus Binding
Pubmed ID 27415624
Reference PloS one, 11(7), e0159074.
Author Memczak, H., Lauster, D., Kar, P., Di Lella, S., Volkmer, R., Knecht, V., Herrmann, A., Ehrentreich-Förster, E., Bier, F. F., & Stöcklein, W. F. (2016).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.