DRAVP ID  DRAVPe02274

Peptide Name   Lunatusin

Sequence  KTCENLADTFRGPCFATSNC

Sequence Length  20

UniProt ID  No entry found

Taxon ID  None

Source  Phaseolus lunatus L. (lima bean)

Validation   Experimentally Validated

Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available

Target Organism  HIV

Assay  ELISA

Activity 

• [Ref:16269344]HIV-1: IC50=120 μM

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity 

• [Ref:16269344]The findings indicate that lunatusin was devoid of cytotoxicity on mammalian splenocytes at concentrations below 50 μM.

Binding Target  Not Found

Mechanism  This 7 kDa isolate can reduce the activity of HIV-1 reverse transcriptase.

PDB ID  None

Predicted Structure Download 

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L

Literature 1

Title   Lunatusin, a trypsin-stable antimicrobial peptide from lima beans (Phaseolus lunatus L.)

Pubmed ID   16269344

Reference   Peptides, 26(11), 2086–2092.

Author   Wong, J. H., & Ng, T. B. (2005).

DOI   10.1016/j.peptides.2005.03.004