General Information


DRAVP ID  DRAVPe02287

Peptide Name   Mytilin B

Sequence  SCASRCKGHCRARRCGYYVSVLYRGRCYCKCLRC

Sequence Length  34

UniProt ID  P81613 

Taxon ID  6550 

Source  Blue mussel, Mytilus edulis and M. galloprovincialis

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  1-34

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  WSSV

Assay  Antiviral Assay

Activity 

  • [Ref:14986940] WSSV:multiplication was prevented by the preincubation with 10 or 50 lm mytilin.

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not Found

Mechanism  Not Available



Structure Information


PDB ID  None

Predicted Structure Download 

Linear/Cyclic  Linear

N-terminal Modification  Amidation

C-terminal Modification  Carboxylation

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  C163H267N59O42S8

Absent amino acids  DEFIMNOPQTUW

Common amino acids  C

Mass  3981.76

Pl  9.58

Basic residues  9

Acidic residues  0

Hydrophobic residues  6

Net charge  9

Boman Index  2.83

Hydrophobicity  -0.344

Aliphatic Index  45.88

Half Life 

  •     Mammalian:1.9hours
  •     Yeast:>20hours
  •     E.coli:>10hours

Extinction Coefficient cystines  6460

Absorbance 280nm  1.622

Polar residues  25



Literature Information


Literature 1

Title   A synthetic antibacterial peptide from Mytilus galloprovincialis reduces mortality due to white spot syndrome virus in palaemonid shrimp

Pubmed ID   14986940

Reference   Journal of fish diseases, 27(1), 57–64.

Author   Dupuy, J. W., Bonami, J. R., & Roch, P. (2004)

DOI   10.1046/j.1365-2761.2003.00516.x