General Information
DRAVP ID DRAVPe02299
Peptide Name SA-hepcidin2
Sequence NPAGCRFCCGCCPNMIGCGVCCRF
Sequence Length 24
UniProt ID A0A142LQX2
Taxon ID None
Source Liver, spotted scat, Scatophagus argus
Validation Experimentally Validated
Origin Information
Gene Name/ID Hepcidin(protein)
GenBank Not Available
Amino Acid position 65-88
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SCRV, MsReV
Assay Antiviral Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Found
Mechanism direct effects on the virion and effects on the innate and adaptive immunity of target cells
Structure Information
PDB ID None
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C99H156N32O27S9
Absent amino acids DEHKLOQSTUWY
Common amino acids C
Mass 2515.07
Pl 8.23
Basic residues 2
Acidic residues 0
Hydrophobic residues 6
Net charge 2
Boman Index 0.41
Hydrophobicity 0.717
Aliphatic Index 32.5
Half Life
Extinction Coefficient cystines 500
Absorbance 280nm 0.199
Polar residues 12
Literature Information
Literature 1
Title Two hepcidins from spotted scat (Scatophagus argus) possess antibacterial and antiviral functions in vitro
Pubmed ID 26845697
Reference Fish & shellfish immunology, 50, 191–199.
Author Gui, L., Zhang, P., Zhang, Q., & Zhang, J. (2016).