To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02303
Peptide Name SmHep1P
Sequence QSHISLCRWCCNCCKANKGCGFCCKF
Sequence Length 26
UniProt ID Q52PA0
Taxon ID 52904
Source Turbot, Scophthalmus maximus
Validation Experimentally Validated
Origin Information
Gene Name/ID hamp
GenBank AAX92670.1
Amino Acid position 65-90
Domain Accession ID Not Available
Nucleotide sequence ID CM023543.1
Molecular Type mRNA
Chromosomal Position Primary_assembly 1: 14,423,721-14,424,529 forward strand.
Activity Information
Target Organism MV
Assay Antiviral Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Found
Mechanism These peptides inhibit viral propagation by disruption of the viral envelope and/or capsid
Structure Information
PDB ID None
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C121H188N38O32S8
Absent amino acids DEMOPTUVY
Common amino acids C
Mass 2943.54
Pl 8.75
Basic residues 4
Acidic residues 0
Hydrophobic residues 6
Net charge 4
Boman Index 1.14
Hydrophobicity 0.096
Aliphatic Index 33.85
Half Life
Extinction Coefficient cystines 6000
Absorbance 280nm 2.038
Polar residues 18
Literature Information
Literature 1
Title Turbot (Scophthalmus maximus) hepcidin-1 and hepcidin-2 possess antimicrobial activity and promote resistance against bacterial and viral infection
Pubmed ID 24647314
Reference Fish & shellfish immunology, 38(1), 127–134.
Author Zhang, J., Yu, L. P., Li, M. F., & Sun, L. (2014).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.