To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02326
Peptide Name DFTavP3
Sequence RWLRGLLSGLLR
Sequence Length 12
UniProt ID No entry found
Taxon ID None
Source Designed In-silico (Ab-initio) by using database filtering technology
Validation In-Silico
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism EBOV
Assay N/A
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Glycoprotein.
Mechanism DFTavP3 likely inhibits Ebola virus infection by targeting specific parameters designed to disrupt viral entry or replication. Its mechanism of action may involve interference with viral attachment, fusion, or replication processes, ultimately reducing viral infectivity. This inhibition could occur through direct interaction with viral components or through modulation of host cell factors essential for viral propagation, leading to decreased viral replication and infection in Vero cells.
Structure Information
PDB ID None
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C66H114N22O14
Absent amino acids ACDEFHIKMNOPQTUVY
Common amino acids L
Mass 1439.77
Pl 12.3
Basic residues 3
Acidic residues 0
Hydrophobic residues 6
Net charge 3
Boman Index 1.61
Hydrophobicity 0.25
Aliphatic Index 162.5
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 3.82
Polar residues 4
Literature Information
Literature 1
Title Improved Database Filtering Technology Enables More Efficient Ab Initio Design of Potent Peptides against Ebola Viruses.
Pubmed ID 35631348
Reference Pharmaceuticals (Basel). 2022;15(5).
Author Ripperda T, Yu Y, Verma A, et al.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.