General Information
DRAVP ID DRAVPe02331
Peptide Name -
Sequence CLHKPWSRC
Sequence Length 9
UniProt ID No entry found
Taxon ID None
Source Phage display
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SNV
Assay Focus reduction assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target beta-3 integrins
Mechanism Blocking of SNV entry into Vero E6 cells
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Cyclic
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H49C74N16O10S2
Absent amino acids ADEFGIMNQTVY
Common amino acids CHKLPRSW
Mass 1129.3584
Pl 8.95718898773193
Basic residues 3
Acidic residues 0
Hydrophobic residues 4
Net charge 1.82646482134686
Boman Index 1.373
Hydrophobicity -0.677777777777777
Aliphatic Index 43.33
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 4.87002177519554
Polar residues 5
Literature Information
Literature 1
Title Peptide antagonists that inhibit Sin Nombre virus and hantaan virus entry through the beta3-integrin receptor.
Pubmed ID 15919886
Reference J Virol. 2005
Author Larson RS, Brown DC, Ye C, Hjelle B.