General Information
DRAVP ID DRAVPe02344
Peptide Name -
Sequence CHARNSTQC
Sequence Length 9
UniProt ID No entry found
Taxon ID None
Source Phage display
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SNV
Assay Focus reduction assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target beta-3 integrins
Mechanism Blocking of SNV entry into Vero E6 cells
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic CyclicÂ
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H225C351N60O59S1
Absent amino acids ACDGHIPY
Common amino acids EFKLMNQRSTVW
Mass 4891.6492
Pl 9.63069019317626
Basic residues 13
Acidic residues 9
Hydrophobic residues 11
Net charge 3.74926253802403
Boman Index 1.868
Hydrophobicity -1.77297297297297
Aliphatic Index 39.46
Half Life
Extinction Coefficient cystines 11000
Absorbance 280nm 2.24873034640342
Polar residues 26
Literature Information
Literature 1
Title Peptide antagonists that inhibit Sin Nombre virus and hantaan virus entry through the beta3-integrin receptor.
Pubmed ID 15919886
Reference J Virol. 2005
Author Larson RS, Brown DC, Ye C, Hjelle B.