General Information
DRAVP ID DRAVPe02346
Peptide Name -
Sequence CRHNNLHHC
Sequence Length 9
UniProt ID No entry found
Taxon ID None
Source Phage display
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SNV
Assay Focus reduction assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target beta-3 integrins
Mechanism Blocking of SNV entry into Vero E6 cells
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic CyclicÂ
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H143C220N37O37S0
Absent amino acids CDEMPVW
Common amino acids AFGHIKLNQRSTY
Mass 3068.5253
Pl 9.99222888946533
Basic residues 3
Acidic residues 0
Hydrophobic residues 14
Net charge 1.48336278072321
Boman Index 0.697
Hydrophobicity 0.562068965517241
Aliphatic Index 104.48
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 0.485575269658034
Polar residues 15
Literature Information
Literature 1
Title Peptide antagonists that inhibit Sin Nombre virus and hantaan virus entry through the beta3-integrin receptor.
Pubmed ID 15919886
Reference J Virol. 2005
Author Larson RS, Brown DC, Ye C, Hjelle B.