General Information
DRAVP ID DRAVPe02372
Peptide Name -
Sequence CLTDRHRTC
Sequence Length 9
UniProt ID No entry found
Taxon ID None
Source Phage display
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SNV
Assay Focus reduction assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target beta-3 integrins
Mechanism Blocking of SNV entry into Vero E6 cells
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic CyclicÂ
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H86C139N23O25S0
Absent amino acids CEFHIMNQSY
Common amino acids ADGKLPRTVW
Mass 1913.17819999999
Pl 8.74773120880127
Basic residues 2
Acidic residues 1
Hydrophobic residues 7
Net charge 0.760213374230145
Boman Index 0.668
Hydrophobicity 0.00555555555555558
Aliphatic Index 81.11
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 2.87479754891625
Polar residues 11
Literature Information
Literature 1
Title Peptide antagonists that inhibit Sin Nombre virus and hantaan virus entry through the beta3-integrin receptor.
Pubmed ID 15919886
Reference J Virol. 2005
Author Larson RS, Brown DC, Ye C, Hjelle B.