General Information
DRAVP ID DRAVPe02384
Peptide Name -
Sequence CRTLPPILC
Sequence Length 9
UniProt ID No entry found
Taxon ID None
Source Phage display
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SNV
Assay Focus reduction assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target beta-3 integrins
Mechanism Blocking of SNV entry into Vero E6 cells
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic CyclicÂ
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H41C59N13O11S2
Absent amino acids DEFILMNPQRVY
Common amino acids ACGHKSTW
Mass 992.133
Pl 8.06797657012939
Basic residues 2
Acidic residues 0
Hydrophobic residues 4
Net charge 0.826474821246869
Boman Index 1.012
Hydrophobicity -0.344444444444444
Aliphatic Index 11.11
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 5.54361159239739
Polar residues 5
Literature Information
Literature 1
Title Peptide antagonists that inhibit Sin Nombre virus and hantaan virus entry through the beta3-integrin receptor.
Pubmed ID 15919886
Reference J Virol. 2005
Author Larson RS, Brown DC, Ye C, Hjelle B.