General Information
DRAVP ID DRAVPe02489
Peptide Name -
Sequence AFHRYGTTVNCIVEE
Sequence Length 15
UniProt ID P06437
Taxon ID 10306
Source Synthetic construct(derived from HSV-1 B glycoprotein (gB))
Validation Experimentally Validated
Origin Information
Gene Name/ID gB
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID K01760
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HSV
Assay beta-galactosidase activity
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Virus entry
Mechanism His6‐HR1 and GST‐removed‐HR2 were tested for their entry inhibition activity.
Structure Information
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H45C67N10O12S2
Absent amino acids BCDJKLMPQS
Common amino acids AF
Mass 1023.2264
Pl 5.51073360443115
Basic residues 0
Acidic residues 0
Hydrophobic residues 5
Net charge -0.260699367007718
Boman Index 0.66
Hydrophobicity 0.5
Aliphatic Index 86.67
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 1.45617822214126
Polar residues 4
Literature Information
Literature 1
Title Multiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection.
Pubmed ID 19104014
Reference Antimicrob Agents Chemother. 2009
Author Akkarawongsa R, Pocaro NE, Case G, Kolb AW, Brandt CR.