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General Information
DRAVP ID DRAVPe02589
Peptide Name -
Sequence QRRNQLHDLRFADID
Sequence Length 15
UniProt ID P06437
Taxon ID 10306
Source Synthetic construct(derived from HSV-1 B glycoprotein (gB))
Validation Experimentally Validated
Origin Information
Gene Name/ID gB
GenBank Not Available
Amino Acid position 706-720
Domain Accession ID Not Available
Nucleotide sequence ID K01760
Molecular Type Genomic DNA
Chromosomal Position Not Available
Activity Information
Target Organism HSV-
Assay beta-galactosidase activity
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Virus entry
Mechanism peptide derived from the C-terminal end of NS5A protein moderately inhibits the assembly process.Exerts viral interference on hepatitis B virus when HCV and HBV coinfect the same cell, by suppressing HBV gene expression, RNA encapsidation and budding.
Structure Information
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H80C125N29O24S0
Absent amino acids BCDEGHIKLMNOPQSTVW
Common amino acids QR
Mass 1897.0594
Pl 6.76056613922119
Basic residues 4
Acidic residues 3
Hydrophobic residues 5
Net charge -0.146211012829276
Boman Index 1.392
Hydrophobicity -1.4
Aliphatic Index 84.67
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 10
Literature Information
Literature 1
Title Multiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection.
Pubmed ID 19104014
Reference Antimicrob Agents Chemother. 2009
Author Akkarawongsa R, Pocaro NE, Case G, Kolb AW, Brandt CR.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.