General Information
DRAVP ID DRAVPe02630
Peptide Name C3
Sequence RRKKAAVALLKAVLLALAAP
Sequence Length 20
UniProt ID P08620
Taxon ID 9606
Source Synthetic construct(derived from FGF-4 signal sequence)
Validation Experimentally Validated
Origin Information
Gene Name/ID FGF4/2249
GenBank AAB59555.1
Amino Acid position Not Available
Domain Accession ID AAA59473.1
Nucleotide sequence ID CM000673.2
Molecular Type mRNA
Chromosomal Position Chromosome 11: 69,773,312-69,775,084
Activity Information
Target Organism VACV
Assay Plaque assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus entry
Structure Information
PDB ID 1IJT
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H80C122N18O25S1
Absent amino acids FHIMTW
Common amino acids RAL
Mass 1786.0103
Pl 4.05002841949462
Basic residues 1
Acidic residues 4
Hydrophobic residues 7
Net charge -3
Boman Index 0.936
Hydrophobicity 0.166666666666666
Aliphatic Index 123.33
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 8
Literature Information
Literature 1
Title Inhibition of Vaccinia virus entry by a broad spectrum antiviral peptide.
Pubmed ID 19395056
Reference Virology. 2009
Author Altmann SE, Jones JC, Schultz-Cherry S, Brandt CR.