To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02638
Peptide Name C4
Sequence RRKKAAVALLKAVLLAALAP
Sequence Length 20
UniProt ID P08620
Taxon ID 9606
Source Synthetic construct(derived from FGF-4 signal sequence)
Validation Experimentally Validated
Origin Information
Gene Name/ID FGF4/2249
GenBank AAB59555.1
Amino Acid position Not Available
Domain Accession ID AAA59473.1
Nucleotide sequence ID CM000673.2
Molecular Type Genomic DNA
Chromosomal Position Chromosome 11: 69,773,312-69,775,091
Activity Information
Target Organism VACV
Assay Plaque assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus entry
Structure Information
PDB ID 1IJT
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H172C288N47O56S2
Absent amino acids FHIMTW
Common amino acids RLA
Mass 3995.5771
Pl 8.19459247589111
Basic residues 6
Acidic residues 5
Hydrophobic residues 13
Net charge 0.827796067432086
Boman Index 1.156
Hydrophobicity -0.76
Aliphatic Index 89.14
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 0.372912338495483
Polar residues 22
Literature Information
Literature 1
Title Inhibition of Vaccinia virus entry by a broad spectrum antiviral peptide.
Pubmed ID 19395056
Reference Virology. 2009
Author Altmann SE, Jones JC, Schultz-Cherry S, Brandt CR.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.