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General Information
DRAVP ID DRAVPe02642
Peptide Name A4
Sequence RRKKAAVALLPAVLLAKLAP
Sequence Length 20
UniProt ID P08620
Taxon ID 9606
Source Synthetic construct(derived from FGF-4 signal sequence)
Validation Experimentally Validated
Origin Information
Gene Name/ID FGF4/2249
GenBank AAB59555.1
Amino Acid position Not Available
Domain Accession ID AAA59473.1
Nucleotide sequence ID CM000673.2
Molecular Type Genomic DNA
Chromosomal Position Chromosome 11: 69,773,312-69,775,095
Activity Information
Target Organism VACV
Assay Plaque assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus entry
Structure Information
PDB ID 1IJT
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C98H139N29O
Absent amino acids FHIMTW
Common amino acids RLA
Mass 2099.651
Pl 12
Basic residues 5
Acidic residues 0
Hydrophobic residues 13
Net charge 4.757
Boman Index 0.997
Hydrophobicity 0.715
Aliphatic Index 156.5
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Literature Information
Literature 1
Title Inhibition of Vaccinia virus entry by a broad spectrum antiviral peptide.
Pubmed ID 19395056
Reference Virology. 2009
Author Altmann SE, Jones JC, Schultz-Cherry S, Brandt CR.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.