General Information
DRAVP ID DRAVPe02645
Peptide Name A7
Sequence RRKKAAVALLPAVKLALLAP
Sequence Length 20
UniProt ID P08620
Taxon ID 9606
Source Synthetic construct(derived from FGF-4 signal sequence)
Validation Experimentally Validated
Origin Information
Gene Name/ID FGF4/2249
GenBank AAB59555.1
Amino Acid position Not Available
Domain Accession ID AAA59473.1
Nucleotide sequence ID CM000673.2
Molecular Type Genomic DNA
Chromosomal Position Chromosome 11: 69,773,312-69,775,098
Activity Information
Target Organism VACV
Assay Plaque assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus entry
Structure Information
PDB ID 1IJT
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H12C17N3O3S0
Absent amino acids FHIMTW
Common amino acids RLA
Mass 269.296999999999
Pl 5.95498714447021
Basic residues 0
Acidic residues 0
Hydrophobic residues 0
Net charge -0.0414711324216447
Boman Index 0.303
Hydrophobicity -1.2
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 3
Literature Information
Literature 1
Title Inhibition of Vaccinia virus entry by a broad spectrum antiviral peptide.
Pubmed ID 19395056
Reference Virology. 2009
Author Altmann SE, Jones JC, Schultz-Cherry S, Brandt CR.