General Information


DRAVP ID  DRAVPe02649

Peptide Name   38

Sequence  EALMWEGF

Sequence Length  8

UniProt ID  No Entry Found 

Taxon ID  None

Source  Synthetic-Construct

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  VACV

Assay  RT PCR

Activity 

  • [Ref:19428604]VACV:IC50=75% in Flp-In-293 cells

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Membrane

Mechanism  Inhibit Replication



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H99C130N25O25S0

Absent amino acids  NDCPMWYOU

Common amino acids  E

Mass  2089.2671

Pl  6.4212942123413

Basic residues  1

Acidic residues  1

Hydrophobic residues  6

Net charge  0

Boman Index  1.042

Hydrophobicity  -1.22777777777777

Aliphatic Index  27.22

Half Life 

  •     Mammalian:20hours
  •     Yeast:15hours
  •     E.coli:18hours

Extinction Coefficient cystines  13980

Absorbance 280nm  6.69134166713294

Polar residues  12



Literature Information


Literature 1

Title   Inhibition of vaccinia virus replication by peptide aptamers.

Pubmed ID   19428604

Reference   Antiviral Res. 2009

Author   Saccucci L, Crance JM, Colas P, Bickle M, Garin D, Iseni F.

DOI   10.1016/j.antiviral.2009.02.191