General Information


DRAVP ID  DRAVPe02650

Peptide Name   72

Sequence  RQLVLRTR

Sequence Length  8

UniProt ID  No Entry Found 

Taxon ID  None

Source  Synthetic-Construct

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  VACV

Assay  RT PCR

Activity 

  • [Ref:19428604]VACV:IC50=40% in Flp-In-293 cells

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Membrane

Mechanism  Inhibit Replication



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H144C207N38O37S0

Absent amino acids  RNDCPQYVOU

Common amino acids  RL

Mass  3081.4395

Pl  8.51158351898193

Basic residues  4

Acidic residues  1

Hydrophobic residues  14

Net charge  3

Boman Index  0.936

Hydrophobicity  0.162962962962962

Aliphatic Index  86.67

Half Life 

  •     Mammalian:2.8hours
  •     Yeast:2.5hours
  •     E.coli:2.6hours

Extinction Coefficient cystines  8480

Absorbance 280nm  2.75196056907819

Polar residues  13



Literature Information


Literature 1

Title   Inhibition of vaccinia virus replication by peptide aptamers.

Pubmed ID   19428604

Reference   Antiviral Res. 2009

Author   Saccucci L, Crance JM, Colas P, Bickle M, Garin D, Iseni F.

DOI   10.1016/j.antiviral.2009.02.191