To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02655
Peptide Name Inhibitor 4
Sequence CGYKRC
Sequence Length 6
UniProt ID No Entry Found
Taxon ID None
Source Synthetic-Contruct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism DENV 2
Assay Flouroscence spectrtophotometery
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Replication
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H73C122N18O24S1
Absent amino acids RNDQWVOU
Common amino acids CG
Mass 1685.936
Pl 7.91892566680908
Basic residues 1
Acidic residues 0
Hydrophobic residues 8
Net charge 0.448247467120587
Boman Index 0.419
Hydrophobicity 0.876470588235294
Aliphatic Index 108.82
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 0.883782065274127
Polar residues 9
Literature Information
Literature 1
Title Critical effect of peptide cyclization on the potency of peptide inhibitors against Dengue virus NS2B-NS3 protease.
Pubmed ID 22780881
Reference J Med Chem. 2012
Author Xu S, Li H, Shao X, Fan C, Ericksen B, Liu J, Chi C, Wang C.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.