General Information


DRAVP ID  DRAVPe02663

Peptide Name   -

Sequence  RRRRR

Sequence Length  5

UniProt ID  No Entry Found 

Taxon ID  None

Source  Synthetic-Contruct

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  HCMV

Assay  Flouroscence spectrtophotometery

Activity 

  • [Ref:10958789]HCMV:IC50=0.99¬±0.08µM in CHO cells

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Membrane

Mechanism  Not Available



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H65C96N16O23S2

Absent amino acids  HILMFTWV

Common amino acids  R

Mass  1551.69639999999

Pl  4.39697360992431

Basic residues  2

Acidic residues  4

Hydrophobic residues  5

Net charge  -3.15507104279364

Boman Index  1.246

Hydrophobicity  -1.13846153846153

Aliphatic Index  37.69

Half Life 

  •     Mammalian:1.1hours
  •     Yeast:1hours
  •     E.coli:1hours

Extinction Coefficient cystines  1490

Absorbance 280nm  0.960239387034732

Polar residues  8



Literature Information


Literature 1

Title   Polyarginines are potent furin inhibitors.

Pubmed ID   10958789

Reference   J Biol Chem. 2000

Author   Cameron A, Appel J, Houghten RA, Lindberg I.

DOI   10.1074/jbc.M003848200