General Information


DRAVP ID  DRAVPe02665

Peptide Name   P13

Sequence  PPARSSPPMPPNLPPLRRRIILLRFLFH

Sequence Length  28

UniProt ID  No Entry Found 

Taxon ID  None

Source  Synthetic-Contruct

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  RV

Assay  GFP assay

Activity 

  • [Ref:15220414]RV:IC50=High

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Phosphoprotein

Mechanism  Not Available



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H235C386N60O75S0

Absent amino acids  HMTW

Common amino acids  PLR

Mass  5271.9675

Pl  8.10575504302978

Basic residues  14

Acidic residues  13

Hydrophobic residues  9

Net charge  0.780653603857022

Boman Index  1.857

Hydrophobicity  -2.15238095238095

Aliphatic Index  53.33

Half Life 

  •     Mammalian:1.4hours
  •     Yeast:1.2hours
  •     E.coli:1.3hours

Extinction Coefficient cystines  2980

Absorbance 280nm  0.565253863951172

Polar residues  33



Literature Information


Literature 1

Title   Antiviral drug discovery strategy using combinatorial libraries of structurally constrained peptides.

Pubmed ID   15220414

Reference   J Virol. 2004

Author   Real E, Rain JC, Battaglia V, Jallet C, Perrin P, Tordo N, Chrisment P, D'Alayer J, Legrain P, Jacob Y.

DOI   10.1128/JVI.78.14.7410-7417.2004