To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02667
Peptide Name K6-10-B
Sequence HCIYATTNDALIFSV
Sequence Length 15
UniProt ID No Entry Found
Taxon ID None
Source Synthetic-Contruct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HCV
Assay FRET assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Replication
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H132C219N40O27S6
Absent amino acids HKMW
Common amino acids AT
Mass 3009.81589999999
Pl 9.42748584747314
Basic residues 6
Acidic residues 0
Hydrophobic residues 17
Net charge 5.69765867099823
Boman Index 1.076
Hydrophobicity 0.792
Aliphatic Index 109.2
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 0.495046889744984
Polar residues 8
Literature Information
Literature 1
Title High affinity peptide inhibitors of the hepatitis C virus NS3-4A protease refractory to common resistant mutants.
Pubmed ID 22965230
Reference J Biol Chem. 2012
Author Kugler J, Schmelz S, Gentzsch J, Haid S, Pollmann E, van den Heuvel J, Franke R, Pietschmann T, Heinz DW, Collins J.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.