General Information


DRAVP ID  DRAVPe02668

Peptide Name   AvBD3

Sequence  TATQCRIRGGFCRVGSCRFPHIAIGKCATFISCCGRAYEVDALNSVRTSPWLLAPGNNPH

Sequence Length  60

UniProt ID  Q9DG58 

Taxon ID  None

Source  Duck beta defensin

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  DHV

Assay  Neutralization assay

Activity 

  • [Ref:23112840]DHV:IC50=High

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Membrane

Mechanism  Not Available



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H98C177N29O20S0

Absent amino acids  HMW

Common amino acids  CATR

Mass  2099.65139999999

Pl  11.9999677658081

Basic residues  5

Acidic residues  0

Hydrophobic residues  13

Net charge  4.75708461139229

Boman Index  0.919

Hydrophobicity  0.715

Aliphatic Index  156.5

Half Life 

  •     Mammalian:1.0hours
  •     Yeast:1hours
  •     E.coli:1hours

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  7



Literature Information


Literature 1

Title   Identification, expression and activity analyses of five novel duck beta-defensins.

Pubmed ID   23112840

Reference   PLoS One. 2012

Author   Ma D, Zhang K, Zhang M, Xin S, Liu X, Han Z, Shao Y, Liu S.

DOI   10.1371/journal.pone.0047743