General Information


DRAVP ID  DRAVPe02670

Peptide Name   -

Sequence  CHTLPHTKC

Sequence Length  9

UniProt ID  No Entry Found 

Taxon ID  None

Source  Phage display

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  SNV

Assay  Focus reduction assay

Activity 

  • [Ref:18391034]SNV:IC50=35%

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Membrane

Mechanism  Inhibit Virus entry



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H95C167N31O32S0

Absent amino acids  IMWV

Common amino acids  CHT

Mass  2275.5622

Pl  10.2779527664184

Basic residues  5

Acidic residues  2

Hydrophobic residues  4

Net charge  2.73659231110456

Boman Index  1.113

Hydrophobicity  -1.23

Aliphatic Index  53.5

Half Life 

  •     Mammalian:100hours
  •     Yeast:60hours
  •     E.coli:90hours

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  16



Literature Information


Literature 1

Title   Multivalent presentation of antihantavirus peptides on nanoparticles enhances infection blockade.

Pubmed ID   18391034

Reference   Antimicrob Agents Chemother. 2008

Author   Hall PR, Hjelle B, Brown DC, Ye C, Bondu-Hawkins V, Kilpatrick KA, Larson RS.

DOI   10.1128/AAC.01415-07