General Information


DRAVP ID  DRAVPe02671

Peptide Name   Mytilin-A

Sequence  GCASRCKAKCAGRRCKGWASAFRGRCYCKCFRC

Sequence Length  33

UniProt ID  P81612 

Taxon ID  6550 

Source  Mytilin-A

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  HSV 1

Assay  Viral titer

Activity 

  • [Ref:23389903]HSV-1:IC50=High

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Membrane

Mechanism  Inhibit Virus entry



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H45C55N9O10S0

Absent amino acids  HILMTWV

Common amino acids  CARK

Mass  899.987599999999

Pl  5.52500019073486

Basic residues  0

Acidic residues  0

Hydrophobic residues  4

Net charge  -0.239898385810697

Boman Index  0.967

Hydrophobicity  0.585714285714285

Aliphatic Index  55.71

Half Life 

  •     Mammalian:2.8hours
  •     Yeast:2.5hours
  •     E.coli:2.6hours

Extinction Coefficient cystines  5500

Absorbance 280nm  6.11119530980205

Polar residues  3



Literature Information


Literature 1

Title   Peptide inhibitors against herpes simplex virus infections.

Pubmed ID   23389903

Reference   J Pept Sci. 2013

Author   Galdiero S, Falanga A, Tarallo R, Russo L, Galdiero E, Cantisani M, Morelli G, Galdiero M.

DOI   10.1002/psc.2489