General Information
DRAVP ID DRAVPe02674
Peptide Name CAP3720-44ser26
Sequence NQGRHFSGGALIHARFVMTAASCFQ
Sequence Length 25
UniProt ID P20160
Taxon ID None
Source Antimicrobial peptide CAP37
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism AdV
Assay Direct time kill assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Assembly formation
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H38C58N12O12S2
Absent amino acids HW
Common amino acids AG
Mass 957.0856
Pl 8.05824184417724
Basic residues 1
Acidic residues 0
Hydrophobic residues 4
Net charge 0.73929063309228
Boman Index 0.654
Hydrophobicity -0.277777777777777
Aliphatic Index 11.11
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 1.55680954765175
Polar residues 5
Literature Information
Literature 1
Title CAP37-derived antimicrobial peptides have in vitro antiviral activity against adenovirus and herpes simplex virus type 1.
Pubmed ID 19274533
Reference Curr Eye Res. 2009
Author Gordon YJ, Romanowski EG, Shanks RM, Yates KA, Hinsley H, Pereira HA.