General Information


DRAVP ID  DRAVPe02678

Peptide Name   PD3

Sequence  KNGRKLCLDLQAALY

Sequence Length  15

UniProt ID  P83470 

Taxon ID  None

Source  Thrombin-induced platelet-derived protein

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  VACV

Assay  Plaque assay

Activity 

  • [Ref:20347875]VACV:IC50=40µg/ml

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not Available

Mechanism  Multifunctional



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H137C198N36O39S2

Absent amino acids  HMTWV

Common amino acids  LK

Mass  3055.4008

Pl  5.98954524993896

Basic residues  3

Acidic residues  2

Hydrophobic residues  13

Net charge  -1.08342876848449

Boman Index  0.936

Hydrophobicity  -0.0846153846153846

Aliphatic Index  78.85

Half Life 

  •     Mammalian:1.2hours
  •     Yeast:1hours
  •     E.coli:1.1hours

Extinction Coefficient cystines  8480

Absorbance 280nm  2.77541329438678

Polar residues  13



Literature Information


Literature 1

Title   Antiviral activity of selected antimicrobial peptides against vaccinia virus.

Pubmed ID   20347875

Reference   Antiviral Res. 2010

Author   Mohan KV, Rao SS, Atreya CD.

DOI   10.1016/j.antiviral.2010.03.012