To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02680
Peptide Name HCVc11-36
Sequence TKRNTNRRPQDVKFPGGGQIVGGVYL
Sequence Length 26
UniProt ID P26663
Taxon ID None
Source HCV core protein
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HCV
Assay Luciferase assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Replication
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H78C121N28O23S1
Absent amino acids HMW
Common amino acids GRV
Mass 1870.0573
Pl 10.9035539627075
Basic residues 5
Acidic residues 1
Hydrophobic residues 3
Net charge 2.84636856168572
Boman Index 1.293
Hydrophobicity -1.84
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 0.796767029545031
Polar residues 12
Literature Information
Literature 1
Title Hepatitis C virus core-derived peptides inhibit genotype 1b viral genome replication via interaction with DDX3X.
Pubmed ID 20862261
Reference PLoS One. 2010
Author Sun C, Pager CT, Luo G, Sarnow P, Cate JH.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.