General Information


DRAVP ID  DRAVPe02681

Peptide Name   P13

Sequence  CDVIALLACHLNTPSFNTTHYRESWY

Sequence Length  26

UniProt ID  No Entry Found 

Taxon ID  None

Source  Phage display

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  WNV

Assay  Q-PCR

Activity 

  • [Ref:17151121]WNV:IC50=Low

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Virus entry

Mechanism  Inhibit Virus entry



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H158C230N44O44S3

Absent amino acids  HMW

Common amino acids  LAC

Mass  3566.01109999999

Pl  4.751194190979

Basic residues  3

Acidic residues  4

Hydrophobic residues  13

Net charge  -2.16567273282702

Boman Index  1.138

Hydrophobicity  -0.68

Aliphatic Index  68.33

Half Life 

  •     Mammalian:2.8hours
  •     Yeast:2.5hours
  •     E.coli:2.6hours

Extinction Coefficient cystines  16500

Absorbance 280nm  4.62701868763112

Polar residues  17



Literature Information


Literature 1

Title   Antiviral peptides targeting the west nile virus envelope protein.

Pubmed ID   17151121

Reference   J Virol. 2007

Author   Bai F, Town T, Pradhan D, Cox J, Ashish, Ledizet M, Anderson JF, Flavell RA, Krueger JK, Koski RA, Fikrig E.

DOI   10.1128/JVI.01840-06