General Information


DRAVP ID  DRAVPe02682

Peptide Name   S25

Sequence  WCNWHNIDPWIQLMNRTQADLAEGPPVKEC

Sequence Length  30

UniProt ID  P21530 

Taxon ID  None

Source  CSFV envelope protein (E2)

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  CSFV

Assay  Plaque assay

Activity 

  • [Ref:21400206]CSFV:IC50=42%

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Membrane

Mechanism  Inhibit CSFV entering



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H143C222N39O51S0

Absent amino acids  HMF

Common amino acids  PWN

Mass  3324.562

Pl  4.05002841949462

Basic residues  1

Acidic residues  5

Hydrophobic residues  13

Net charge  -4.22399819814388

Boman Index  0.851

Hydrophobicity  -0.1

Aliphatic Index  104

Half Life 

  •     Mammalian:1.1hours
  •     Yeast:30.0mins
  •     E.coli:54.0mins

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  17



Literature Information


Literature 1

Title   Identification of host cell binding peptide from an overlapping peptide library for inhibition of classical swine fever virus infection.

Pubmed ID   21400206

Reference   Virus Genes. 2011

Author   Li X, Wang L, Zhao D, Zhang G, Luo J, Deng R, Yang Y.

DOI   10.1007/s11262-011-0595-7