General Information


DRAVP ID  DRAVPe02683

Peptide Name   C4

Sequence  CQRCGWETGVGVSGFLVRILRFVVL

Sequence Length  25

UniProt ID  No Entry Found 

Taxon ID  None

Source  Synthetic-Contruct

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  RV

Assay  GFP assay

Activity 

  • [Ref:15220414]RV:IC50=High

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Phosphoprotein

Mechanism  Not Available



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H91C156N26O33S0

Absent amino acids  CHIKMFTW

Common amino acids  VLG

Mass  2160.3819

Pl  6.25651798248291

Basic residues  4

Acidic residues  4

Hydrophobic residues  7

Net charge  -0.200258970315807

Boman Index  1.116

Hydrophobicity  -0.875

Aliphatic Index  83

Half Life 

  •     Mammalian:4.4hours
  •     Yeast:20hours
  •     E.coli:10hours

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  13



Literature Information


Literature 1

Title   Antiviral drug discovery strategy using combinatorial libraries of structurally constrained peptides.

Pubmed ID   15220414

Reference   J Virol. 2004

Author   Real E, Rain JC, Battaglia V, Jallet C, Perrin P, Tordo N, Chrisment P, D'Alayer J, Legrain P, Jacob Y.

DOI   10.1128/JVI.78.14.7410-7417.2004