General Information
DRAVP ID DRAVPe02688
Peptide Name HCVc16-36
Sequence NRRPQDVKFPGGGQIVGGVYL
Sequence Length 21
UniProt ID P26663
Taxon ID None
Source HCV core protein
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HCV
Assay Luciferase assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Replication
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H76C116N27O23S1
Absent amino acids HMW
Common amino acids GVR
Mass 1829.0055
Pl 8.24964847564697
Basic residues 3
Acidic residues 2
Hydrophobic residues 2
Net charge 0.755791548336709
Boman Index 1.306
Hydrophobicity -2.10666666666666
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 13
Literature Information
Literature 1
Title Hepatitis C virus core-derived peptides inhibit genotype 1b viral genome replication via interaction with DDX3X.
Pubmed ID 20862261
Reference PLoS One. 2010
Author Sun C, Pager CT, Luo G, Sarnow P, Cate JH.