To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02689
Peptide Name peptide 57
Sequence RRLQVGGGTLKFFLT
Sequence Length 15
UniProt ID P10226
Taxon ID None
Source HSV UL42 protein
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HSV 1
Assay DNA polymerase assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Replication
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H228C356N48O57S1
Absent amino acids HIMW
Common amino acids GLFTR
Mass 4731.6336
Pl 6.43772068023681
Basic residues 9
Acidic residues 9
Hydrophobic residues 17
Net charge -0.249708461276961
Boman Index 1.599
Hydrophobicity -0.497297297297297
Aliphatic Index 102.7
Half Life
Extinction Coefficient cystines 11000
Absorbance 280nm 2.32477848665205
Polar residues 20
Literature Information
Literature 1
Title Inhibition of herpes simplex virus type 1 DNA polymerase activity by peptides from the UL42 accessory protein is largely nonspecific.
Pubmed ID 8380075
Reference J Virol. 1993
Author Owsianka AM, Hart G, Murphy M, Gottlieb J, Boehme R, Challberg M, Marsden HS.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.